مقاله تحقیقی Liposomal Iron

Abstract
Iron deficiency anemia is the most frequent nutritional deficiency disorder.
Conventionally administered oral iron is associated with gastrointestinal intolerance that affects the outcomes and compliance. Liposomal iron is associated with increased absorption without causing significant adverse effects.
In this review, we have discussed the technology of liposomal iron preparation, mechanisms of its absorption and clinical evidence on its utility in iron
deficiency states in pregnant and non-pregnant women. Based on the available evidence, we compared liposomal iron to conventional oral iron. Encapsulation of micronized iron in liposomes is associated with lesser exposure to
gastric contents, lesser interaction with food contents, no exposure to different digestive juices, targeted delivery of iron and allows lower doses to be
administered in lieu of direct absorption without need for protein carriers.
The available evidence suggests that liposomal iron significantly increases
hemoglobin, ferritin levels in pregnant women as well as in women with iron
deficiency.
Keywords
Liposomal Iron, Microencapsulated, Micronized, Iron Deficiency, Anemia,
Pregnancy

 

 

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